nature :press: on Nostr: Enhancing transcription–replication conflict targets ecDNA-positive cancers Nature, ...

Enhancing transcription–replication conflict targets ecDNA-positive cancers

Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-07802-5Extrachromosomal DNA makes cancerous tumours resistant to treatment, but this research demonstrates that increasing transcription–replication conflict allows for targeted elimination of cancer cells containing extrachromosomal DNA, and thus sustained tumour... #press

https://www.nature.com/articles/s41586-024-07802-5?utm_source=press.coop