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chrispatrick / Chris Patrick
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2025-02-16 02:22:02

chrispatrick on Nostr: What is causing Metabolic Syndrome & Obesity? Mitochondrial Dysfunction → Leptin ...

What is causing Metabolic Syndrome & Obesity?

Mitochondrial Dysfunction → Leptin Resistance → Fat Storage

This leads to two pathways:

1. Low Personal Fat Threshold → Cannot store more fat → Insulin Resistance → Metabolic Syndrome

2. High Personal Fat Threshold → Can store more fat → Insulin Sensitive → Obesity (Then eventually Metabolic Syndrome)
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