whygetfat on Nostr: Abel James: "What exactly is blue light doing when you're looking at it? Because I ...
Abel James: "What exactly is blue light doing when you're looking at it? Because I think a lot of people can relate to the feeling of scrolling mindlessly […] I'm guilty of this as well […] you're in a state that is absolutely suboptimal, but you can't get away from it. What exactly is going on […]
Dr. Jack Kruse: "All right, I'm going to give it to you very, very fast and I'm not going to get into the details. The process that causes this is called ferroptosis, probably something you've never heard about before. It's behind most of the microvascular changes that happen. It's a quantum-level effect through an iron atom with the interaction with blue light. […]
"But what effectively happens? Blue light has a non-visual photoreceptor called melanopsin. Melanopsin we found in the early 2000s. Then in the 2000s, we found out not only is in our subQ fat, it's in our arteries, it's in our brain. In fact, it's the number one dominant chromophore in the body. It reacts to the blue light spectrum, specifically between 435 and 470. And what happens?
"Every opsin, anytime you hear the word opsin, whether it's rhodopsin, melanopsin, neuropsin, encephalopsin, they're always bound to vitamin A called retinol. When light hits that protein retinol gets freed. Freed retinol has to be resorbed and recycled immediately. Why? Because it's toxic.
"So what does the vitamin A do? It destroys the photoreceptors. Hard stop. Now you have the mechanism.
"How does nature offset this? Because you're like, 'Jack, there's blue light in the sun, so there's got to be a program.' There is. The program in the eye is called Bazan's loop, short and long loop. What effectively happens, we recycle the vitamin A very, very quickly so it doesn't hurt us.
"What's the two chemicals that regenerate all the non-visual photoreceptors? Dopamine and melatonin. Ho! There you go!
"So melatonin, everybody […] would tell you, 'Oh, it's in your pineal gland.' No, it's actually made in your mitochondria. It turns out the mitochondria in that leptin-melanocortin pathway, […] that's the pathway that gets destroyed.
"And what happens is the problem starts first in the retina, gets generalized through the rest of the brain. Wherever the brain gets damaged that's the disease that you get. That's effectively how it happens.
"So it's a problem of vitamin A. […] (Chris MasterJohn, when he used to work for the Weston A Price foundation, he did a really nice paper a long time ago about the effects of vitamin A, that when vitamin A goes awry it ruins your sleep.) […]
"Vitamin A is a real problem when it comes to blue light. It destroys your ability to regenerate your photoreceptors. So when you regenerate the photoreceptor you can't, you need to chronically have this blue light hit for the dopamine problem. Guess where it goes?
"The leptin-melanocortin pathway has two major places that it goes with no synapses. The first one I think you know: SCN, that's the suprachiasmatic nucleus. That's what I tried to bring to the world 20 years ago when you first met me.
"Where's the other place it goes? The habenular nucleus in the hypothalamus and the thalamus. That's the relay center for the frontal lobes. Those are the two lobes that we got that our cousins don't have. This is the reason why mental illness, depression, you know addictive behaviors, obesity, that's where it's all coming from. That's where the reward tracts are. […]
"And when this disruption happens, you constantly need more and more and more. It's what you just said to your audience. That when you sit in front of blue light all day, or you're playing your music in front of blue light, you get depressed. […]
"And it turns out all the non-visual photoreceptors that get destroyed like this tend to be heme based. let me say that again. Heme based, like hemoglobin. Why?
"Because it turns out there's a very specific action spectra, 250 to 600 nm light, that's red light. Red light is the antidote to blue.
"So guess what? In the sun that's behind me, you never get blue by itself. You always get the antidote with it. That's the reason why blue light from the sun is not like blue light from your device. Guess what?
"That's the information the CIA, the FBI, and MKUltra taught the government. That's the reason why they've subtracted out the red and the UV. Because guess what? That will help save you. Got it?"
Dr. Jack Kruse with Abel James @ 01:18:58–01:24:52 https://youtu.be/zik08V9waJk&t=4738
Dr. Jack Kruse: "All right, I'm going to give it to you very, very fast and I'm not going to get into the details. The process that causes this is called ferroptosis, probably something you've never heard about before. It's behind most of the microvascular changes that happen. It's a quantum-level effect through an iron atom with the interaction with blue light. […]
"But what effectively happens? Blue light has a non-visual photoreceptor called melanopsin. Melanopsin we found in the early 2000s. Then in the 2000s, we found out not only is in our subQ fat, it's in our arteries, it's in our brain. In fact, it's the number one dominant chromophore in the body. It reacts to the blue light spectrum, specifically between 435 and 470. And what happens?
"Every opsin, anytime you hear the word opsin, whether it's rhodopsin, melanopsin, neuropsin, encephalopsin, they're always bound to vitamin A called retinol. When light hits that protein retinol gets freed. Freed retinol has to be resorbed and recycled immediately. Why? Because it's toxic.
"So what does the vitamin A do? It destroys the photoreceptors. Hard stop. Now you have the mechanism.
"How does nature offset this? Because you're like, 'Jack, there's blue light in the sun, so there's got to be a program.' There is. The program in the eye is called Bazan's loop, short and long loop. What effectively happens, we recycle the vitamin A very, very quickly so it doesn't hurt us.
"What's the two chemicals that regenerate all the non-visual photoreceptors? Dopamine and melatonin. Ho! There you go!
"So melatonin, everybody […] would tell you, 'Oh, it's in your pineal gland.' No, it's actually made in your mitochondria. It turns out the mitochondria in that leptin-melanocortin pathway, […] that's the pathway that gets destroyed.
"And what happens is the problem starts first in the retina, gets generalized through the rest of the brain. Wherever the brain gets damaged that's the disease that you get. That's effectively how it happens.
"So it's a problem of vitamin A. […] (Chris MasterJohn, when he used to work for the Weston A Price foundation, he did a really nice paper a long time ago about the effects of vitamin A, that when vitamin A goes awry it ruins your sleep.) […]
"Vitamin A is a real problem when it comes to blue light. It destroys your ability to regenerate your photoreceptors. So when you regenerate the photoreceptor you can't, you need to chronically have this blue light hit for the dopamine problem. Guess where it goes?
"The leptin-melanocortin pathway has two major places that it goes with no synapses. The first one I think you know: SCN, that's the suprachiasmatic nucleus. That's what I tried to bring to the world 20 years ago when you first met me.
"Where's the other place it goes? The habenular nucleus in the hypothalamus and the thalamus. That's the relay center for the frontal lobes. Those are the two lobes that we got that our cousins don't have. This is the reason why mental illness, depression, you know addictive behaviors, obesity, that's where it's all coming from. That's where the reward tracts are. […]
"And when this disruption happens, you constantly need more and more and more. It's what you just said to your audience. That when you sit in front of blue light all day, or you're playing your music in front of blue light, you get depressed. […]
"And it turns out all the non-visual photoreceptors that get destroyed like this tend to be heme based. let me say that again. Heme based, like hemoglobin. Why?
"Because it turns out there's a very specific action spectra, 250 to 600 nm light, that's red light. Red light is the antidote to blue.
"So guess what? In the sun that's behind me, you never get blue by itself. You always get the antidote with it. That's the reason why blue light from the sun is not like blue light from your device. Guess what?
"That's the information the CIA, the FBI, and MKUltra taught the government. That's the reason why they've subtracted out the red and the UV. Because guess what? That will help save you. Got it?"
Dr. Jack Kruse with Abel James @ 01:18:58–01:24:52 https://youtu.be/zik08V9waJk&t=4738