Nicole Rust on Nostr: Looking for: drugs developed using systems biology / complex systems (probably ...
Looking for: drugs developed using systems biology / complex systems (probably cancer).
I'm looking for examples in which the appreciation that a genetic network is configured (not as a domino chain but) as a complex system led to the identification of a therapeutic target and a new drug.
I know that there are examples of that we can point to explaining 1) why existing drugs don't work or 2) are in the clinical pipeline (eg clinical trials). But do you know of any "success stories" that are approved and in use?
Anything in the "brain" space is particularly appreciated!
I'm looking for examples in which the appreciation that a genetic network is configured (not as a domino chain but) as a complex system led to the identification of a therapeutic target and a new drug.
I know that there are examples of that we can point to explaining 1) why existing drugs don't work or 2) are in the clinical pipeline (eg clinical trials). But do you know of any "success stories" that are approved and in use?
Anything in the "brain" space is particularly appreciated!