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Holly A. Gultiano /
npub12gv…55ru
2025-01-18 09:03:32
in reply to nevent1q…vf4m

Holly A. Gultiano on Nostr: nprofile1q…f7c02 This is one of those news articles that talks about research but ...

nprofile1qy2hwumn8ghj7un9d3shjtnddaehgu3wwp6kyqpqnac93fnqmsjtx77s6mmlgvprmx9dpd09g75dyql3juq2utlslxkqvf7c02 (nprofile…7c02) This is one of those news articles that talks about research but doesn't link to it. Here it is https://www.cell.com/cell/fulltext/S0092-8674(24)01379-5

I wanted to know if it applies to other CAG-polyglutamine repeat diseases like some of the spinocerebellar ataxias. "The dynamic we have described, in which the toxic effect of a DNA repeat is acquired only after decades of somatic expansion, could in principle also apply in other DNA-repeat disorders"
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