Levka on Nostr: #aging #gender "Snyder and his colleagues noticed that there's a very clear change in ...
#aging #gender
"Snyder and his colleagues noticed that there's a very clear change in the abundance of many different kinds of molecules in the human body at two distinct stages.
Around 81 percent of all the molecules they studied showed changes during one or both of these stages. Changes peaked in the mid-40s, and again in the early 60s, with slightly different profiles.
The mid-40s peak showed changes in molecules related to the metabolism of lipids, caffeine, and alcohol, as well as cardiovascular disease, and dysfunctions in skin and muscle.
The early 60s peak was associated with carbohydrate and caffeine metabolism, cardiovascular disease, skin and muscle, immune regulation, and kidney function.The first peak, the mid-40s, is typically when women start undergoing menopause or perimenopause, but the researchers ruled this out as a main factor: men, too, also underwent significant molecular changes at the same age.
'This suggests that while menopause or perimenopause may contribute to the changes observed in women in their mid-40s, there are likely other, more significant factors influencing these changes in both men and women,' explained metabolomicist and first author Xiaotao Shen, formerly of Stanford, now at Nanyang Technological University Singapore."
https://www.sciencealert.com/study-finds-humans-age-faster-at-2-sharp-peaks-heres-when-they-hit
"Snyder and his colleagues noticed that there's a very clear change in the abundance of many different kinds of molecules in the human body at two distinct stages.
Around 81 percent of all the molecules they studied showed changes during one or both of these stages. Changes peaked in the mid-40s, and again in the early 60s, with slightly different profiles.
The mid-40s peak showed changes in molecules related to the metabolism of lipids, caffeine, and alcohol, as well as cardiovascular disease, and dysfunctions in skin and muscle.
The early 60s peak was associated with carbohydrate and caffeine metabolism, cardiovascular disease, skin and muscle, immune regulation, and kidney function.The first peak, the mid-40s, is typically when women start undergoing menopause or perimenopause, but the researchers ruled this out as a main factor: men, too, also underwent significant molecular changes at the same age.
'This suggests that while menopause or perimenopause may contribute to the changes observed in women in their mid-40s, there are likely other, more significant factors influencing these changes in both men and women,' explained metabolomicist and first author Xiaotao Shen, formerly of Stanford, now at Nanyang Technological University Singapore."
https://www.sciencealert.com/study-finds-humans-age-faster-at-2-sharp-peaks-heres-when-they-hit