trendless on Nostr: ...
https://medicalxpress.com/news/2024-02-dangerous-pregnancy-complications-linked-covid.html
> DNA changes consistent with life-threatening pregnancy complications have been found in the placentas of pregnant women infected by COVID-19, according to University of Queensland researchers. Their research paper is published in Clinical and Translational Immunology.
"Using digital spatial profiling, we discovered the virus disrupts placental function by altering the genomic architecture of the cells critical to providing nutrients and blood supply to unborn babies. We also found the DNA fingerprints of poor placental oxygenation, stress and pre-eclampsia in the COVID-19 patients."
🔗 Nataly Stylianou et al, Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures, Clinical & Translational Immunology (2024). DOI: 10.1002/cti2.1488
> We utilised whole-transcriptome, digital spatial profiling, to examine gene expression patterns in placental tissues from participants who contracted SARS-CoV-2 in the third trimester of their pregnancy (n = 7) and those collected prior to the start of the coronavirus disease 2019 (COVID-19) pandemic (n = 9).
> DNA changes consistent with life-threatening pregnancy complications have been found in the placentas of pregnant women infected by COVID-19, according to University of Queensland researchers. Their research paper is published in Clinical and Translational Immunology.
"Using digital spatial profiling, we discovered the virus disrupts placental function by altering the genomic architecture of the cells critical to providing nutrients and blood supply to unborn babies. We also found the DNA fingerprints of poor placental oxygenation, stress and pre-eclampsia in the COVID-19 patients."
🔗 Nataly Stylianou et al, Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures, Clinical & Translational Immunology (2024). DOI: 10.1002/cti2.1488
> We utilised whole-transcriptome, digital spatial profiling, to examine gene expression patterns in placental tissues from participants who contracted SARS-CoV-2 in the third trimester of their pregnancy (n = 7) and those collected prior to the start of the coronavirus disease 2019 (COVID-19) pandemic (n = 9).