李老师不是你老师 on Nostr: ...
1月初，来自北京市知名中学的化学老师曹葵对经济观察报表示，高中化学的一个必做实验中的异常现象令他困惑。该实验涉及了一款知名药物——阿司匹林肠溶片，自两年前实验所用阿司匹林肠溶片更换了品牌之后，实验效果出现了肉眼可见的差异。
据他介绍，阿司匹林肠溶片检测实验是高二化学课的一项必做实验。目的是检测阿司匹林有效成分乙酰水杨酸中的羧基和酯基。在酯基检验中，需要先对乙酰水杨酸进行水解，水解后会产生水杨酸。当水杨酸遇到氯化铁，会发生变色反应，溶液呈现紫色。
现在，由于水解实验前后，溶液都发生了变色，这个环节失去了意义，并且上述现象是普遍的，学生操作和老师操作的结果一致。
In early January, Cao Kui, a chemistry teacher from a prestigious high school in Beijing, expressed his confusion to the Economic Observer about an anomaly in a mandatory high school chemistry experiment. The experiment involves a well-known medication - enteric-coated aspirin tablets. Since changing the brand of enteric-coated aspirin two years ago, there has been a visible difference in the experimental results.
According to him, the enteric-coated aspirin testing experiment is mandatory in second-year high school chemistry courses. The purpose is to detect the carboxyl and ester groups in acetylsalicylic acid, the active ingredient in aspirin. In the ester group test, acetylsalicylic acid must first undergo hydrolysis, which produces salicylic acid. When salicylic acid meets ferric chloride, a color change reaction occurs, turning the solution purple.
Now, since the solution changes color both before and after hydrolysis, this experimental step has become meaningless. Moreover, this phenomenon is widespread, with both students and teachers obtaining the same results.
据他介绍，阿司匹林肠溶片检测实验是高二化学课的一项必做实验。目的是检测阿司匹林有效成分乙酰水杨酸中的羧基和酯基。在酯基检验中，需要先对乙酰水杨酸进行水解，水解后会产生水杨酸。当水杨酸遇到氯化铁，会发生变色反应，溶液呈现紫色。
现在，由于水解实验前后，溶液都发生了变色，这个环节失去了意义，并且上述现象是普遍的，学生操作和老师操作的结果一致。
In early January, Cao Kui, a chemistry teacher from a prestigious high school in Beijing, expressed his confusion to the Economic Observer about an anomaly in a mandatory high school chemistry experiment. The experiment involves a well-known medication - enteric-coated aspirin tablets. Since changing the brand of enteric-coated aspirin two years ago, there has been a visible difference in the experimental results.
According to him, the enteric-coated aspirin testing experiment is mandatory in second-year high school chemistry courses. The purpose is to detect the carboxyl and ester groups in acetylsalicylic acid, the active ingredient in aspirin. In the ester group test, acetylsalicylic acid must first undergo hydrolysis, which produces salicylic acid. When salicylic acid meets ferric chloride, a color change reaction occurs, turning the solution purple.
Now, since the solution changes color both before and after hydrolysis, this experimental step has become meaningless. Moreover, this phenomenon is widespread, with both students and teachers obtaining the same results.