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Thiago Carvalho /
npub1xak…zham
2024-07-29 11:37:58

Thiago Carvalho on Nostr: 'We demonstrate the first generalizable strategy using a small molecule to ...

'We demonstrate the first generalizable strategy using a small molecule to selectively kill TP53 mutant cells. This molecule binds the Y220C mutant of p53 and concentrates a PLK1 inhibitor in cells harboring TP53 Y220C mutations.'
#Preprint
https://www.biorxiv.org/content/10.1101/2024.07.27.605429v1
Author Public Key
npub1xakev87fgm9edqu6f5jhszwunekjxl3dpnq4sxvm3nzu2ace8xnqyczham