mittimithai on Nostr: I figured she meant something like that and it is certainly a tempting perspective ...
I figured she meant something like that and it is certainly a tempting perspective (and may be right), but as far as I know, it's more correct to say something like what Arnold said here (i.e. conceding the bias towards androgenization and acknowledging that it is difficult to disentangle from environment, even in "natural experiments" like CAIS):
> A knockout of the androgen receptor in XY individuals (complete androgen insensitivity syndrome [CAIS] in humans) alters the body so that it looks completely like that of a female, proving that the masculine structure of many reproductive tissues requires androgen action in males. However, because the XY CAIS girl is reared as a female, one cannot easily separate the biologically and socially mediated effects of the mutation on many attributes that one might measure in CAIS women—for example, their brain function or susceptibility to disease (e.g., Hamann et al., 2014). In addition, differences in social or physical environments are expected to have lasting effects on the epigenome (DNA methylation and modifications of histones), so that the environment alters the readout of the genome (Szyf et al., 2008). One way or another, the effects of the environment on an individual are mediated by changes in the person's biology, making it difficult to disentangle the two sources of variation. Much of the argument, about whether social or biological factors cause sex differences in physiology and disease, may be based as much on which factors a specific author finds to be interesting or preferable rather than on any evidence that effects of one factor can be dissociated from effects of others and found to be more important. The environmentalist and biologist are both susceptible to the mistake of overgeneralizing the importance of factors that they are trained to study or prefer. The theory of sexual differentiation, presented below, focuses exclusively on the biological factors that make females and males different from each other. This focus comes with the acknowledgment that sex-biasing factors are also found in the social and physical environments.
https://onlinelibrary.wiley.com/doi/full/10.1002/jnr.23884?fbclid=IwY2xjawIEA4RleHRuA2FlbQIxMQABHS0G-Q9x7HpURpC73zCYT8j6MnPhQFlEeZPlFypGImefBPiv62LFRw-Vdg_aem_aC2HLVymbLKJS-b6qnyviQ
> A knockout of the androgen receptor in XY individuals (complete androgen insensitivity syndrome [CAIS] in humans) alters the body so that it looks completely like that of a female, proving that the masculine structure of many reproductive tissues requires androgen action in males. However, because the XY CAIS girl is reared as a female, one cannot easily separate the biologically and socially mediated effects of the mutation on many attributes that one might measure in CAIS women—for example, their brain function or susceptibility to disease (e.g., Hamann et al., 2014). In addition, differences in social or physical environments are expected to have lasting effects on the epigenome (DNA methylation and modifications of histones), so that the environment alters the readout of the genome (Szyf et al., 2008). One way or another, the effects of the environment on an individual are mediated by changes in the person's biology, making it difficult to disentangle the two sources of variation. Much of the argument, about whether social or biological factors cause sex differences in physiology and disease, may be based as much on which factors a specific author finds to be interesting or preferable rather than on any evidence that effects of one factor can be dissociated from effects of others and found to be more important. The environmentalist and biologist are both susceptible to the mistake of overgeneralizing the importance of factors that they are trained to study or prefer. The theory of sexual differentiation, presented below, focuses exclusively on the biological factors that make females and males different from each other. This focus comes with the acknowledgment that sex-biasing factors are also found in the social and physical environments.
https://onlinelibrary.wiley.com/doi/full/10.1002/jnr.23884?fbclid=IwY2xjawIEA4RleHRuA2FlbQIxMQABHS0G-Q9x7HpURpC73zCYT8j6MnPhQFlEeZPlFypGImefBPiv62LFRw-Vdg_aem_aC2HLVymbLKJS-b6qnyviQ