Redish Lab on Nostr: nprofile1q…hcvwk 2/2 In terms of spikes and rates, it clearly depends on the ...
nprofile1qy2hwumn8ghj7un9d3shjtnddaehgu3wwp6kyqpq9d9p04u4xfysdy92fycw947jrca3xve2gnsauysshzewxvmz8dmsxhcvwk (nprofile…cvwk) 2/2
In terms of spikes and rates, it clearly depends on the structure involved. For some structures, we know that spike timing is critical. (For example, in hippocampus, spike timing relative to the theta rhythm carries information beyond the average rate. We know that these two signals are dissociable - that is, one can maintain the place field while losing the theta-spike timing and the neural sequence. In fact, we know that all three signals (place field, spike timing relative to theta, neural sequences) are dissociable.)
The best description of the spike timing debate I heard was Stuart Geman who asked "if you add temporal noise to the spike, how much temporal noise can you add without losing the important information?" Seconds is almost certainly too much. Nanoseconds almost certainly fine. By ms? us? cs? Almost certainly depends on structure.
So, in my view, the spike rate debate isn't so much settled as progressed scientifically.
In terms of spikes and rates, it clearly depends on the structure involved. For some structures, we know that spike timing is critical. (For example, in hippocampus, spike timing relative to the theta rhythm carries information beyond the average rate. We know that these two signals are dissociable - that is, one can maintain the place field while losing the theta-spike timing and the neural sequence. In fact, we know that all three signals (place field, spike timing relative to theta, neural sequences) are dissociable.)
The best description of the spike timing debate I heard was Stuart Geman who asked "if you add temporal noise to the spike, how much temporal noise can you add without losing the important information?" Seconds is almost certainly too much. Nanoseconds almost certainly fine. By ms? us? cs? Almost certainly depends on structure.
So, in my view, the spike rate debate isn't so much settled as progressed scientifically.