Thiago Carvalho on Nostr: Tools: "Here, we introduce a novel in vitro cultivation system based on ThymoSpheres ...
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"Here, we introduce a novel in vitro cultivation system based on ThymoSpheres (TS): dense spheroids consisting of DLL4-expressing stromal cells and human hematopoietic precursor cells, in the absence of thymic epithelial cells. These spheroids are subsequently cultured at the air–liquid interphase. TS generate large numbers of mature T cells, are easy to manipulate, scalable, and can be repeatably sampled to monitor T-cell differentiation."
#Immunology
https://onlinelibrary.wiley.com/doi/full/10.1002/eji.202451265
"Here, we introduce a novel in vitro cultivation system based on ThymoSpheres (TS): dense spheroids consisting of DLL4-expressing stromal cells and human hematopoietic precursor cells, in the absence of thymic epithelial cells. These spheroids are subsequently cultured at the air–liquid interphase. TS generate large numbers of mature T cells, are easy to manipulate, scalable, and can be repeatably sampled to monitor T-cell differentiation."
#Immunology
https://onlinelibrary.wiley.com/doi/full/10.1002/eji.202451265