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2023-12-28 13:46:14

David Meyer on Nostr: This paper describes the predatory bacterium Vampirococcus lugosii, which preys on ...

This paper describes the predatory bacterium Vampirococcus lugosii, which preys on members of the bacterial species of the genus Halochromatium [1].

This thing is incredible. For example: Vampirococcus lugosii has a severely reduced genome, something like 1.3 Mbp, and lacks the genes which code for many of the standard biosynthetic metabolic pathways (e.g. phospholipid synthesis, amino acid synthesis, and nucleotide synthesis). Yet it is somehow still alive.

How does this work?

One mechanism that Vampirococcus uses is to get these raw materials from its prey. An example of this are the nucleotides that Vampirococcus lugosii gets by chopping up the DNA that it sucks out of its prey. And amazingly, Vampirococcus lugosii uses a CRISPR-Cas system and various restriction enzymes to accomplish this. See the image for a cartoon of this system.

Predatory microbes.

Crazy.

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Description of “Candidatus Vampirococcus lugosii”]

Lugosii after Bela Lugosi (1882–1956), who played the role of the vampire in the iconic 1931’s film “Dracula”. Epibiotic bacterium that preys on anoxygenic photosynthetic gammaproteobacterial species of the genus Halochromatium. Non-flagellated, small flat rounded cells (500–600 nm diameter and 200–250 nm height) that form piles of up to 10 cells attached to the surface of the host. Gram-positive cell wall structure. Complete genome sequence, GenBank/EMBL/DDBJ accession number PRJNA678638.
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#biology #vampirococcuslugosii

References
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[1] "Reductive evolution and unique infection and feeding mode in the CPR predatory bacterium Vampirococcus lugosii", https://www.nature.com/articles/s41467-021-22762-4

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