Thiago Carvalho on Nostr: 'We found that up-regulation of a primate-specific short isoform of PRDM1-S induces ...
'We found that up-regulation of a primate-specific short isoform of PRDM1-S induces expression of SGK1 independent from the evolutionarily conserved long PRDM1, which led to destabilization of #FOXP3 & #Treg dysfunction. This aberrant PRDM1-S/SGK1 axis is shared among other autoimmune diseases.'
#Immunology
https://www.science.org/doi/10.1126/scitranslmed.adp1720Published at
2024-08-29 09:13:50Event JSON
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