Can Knicks' defense hold up with Karl-Anthony Towns at center?

Can Knicks' defense hold up with Karl-Anthony Towns at center?
https://media.zenfs.com/en/sny_articles_235/f7b47d0d4bdc4b40f9fa597ac30ebf8b

The Knicks will have to get the best out of Karl-Anthony Towns on the defensive end to get where they want to be this season.

https://sports.yahoo.com/knicks-defense-hold-karl-anthony-150004407.html