Thiago Carvalho on Nostr: 'As mice age, IL-11 is upregulated across cell types and tissues to regulate an ...
'As mice age, IL-11 is upregulated across cell types and tissues to regulate an ERK–AMPK–mTORC1 axis to modulate cellular, tissue- and organismal-level ageing pathologies. Deletion of Il11 or Il11ra1 protects against metabolic decline, multi-morbidity and frailty in old age.'
#Immunology
https://www.nature.com/articles/s41586-024-07701-9Published at
2024-07-18 07:33:39Event JSON
{
"id": "7ae8dcd46b372b60a6b6d15096ee01a16ce7432f758bbf034ea6d6f9efc487e1",
"pubkey": "376d961fc946cb96839a4d257809dc9e6d237e2d0cc158199b8cc5c5771939a6",
"created_at": 1721288019,
"kind": 1,
"tags": [
[
"t",
"immunology"
],
[
"proxy",
"https://qoto.org/users/cyrilpedia/statuses/112806331634468096",
"activitypub"
]
],
"content": "'As mice age, IL-11 is upregulated across cell types and tissues to regulate an ERK–AMPK–mTORC1 axis to modulate cellular, tissue- and organismal-level ageing pathologies. Deletion of Il11 or Il11ra1 protects against metabolic decline, multi-morbidity and frailty in old age.'\n#Immunology \n\nhttps://www.nature.com/articles/s41586-024-07701-9",
"sig": "4ad6c561cbd0d6b42f1a9e237e05ae1180e126923e00c93f19b33ff258cf9839e9b96a0fb257ee83af4e646443ca68b572a9b64c1cacd15ee644914f0af75354"
}
