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"content": "Sorry. I wasnt super-clear in explanation.\n\nWas assuming a total market potential of $1B per year, but assumed the successful drug would only capture 50% of that market averaged over 16 years.\n\nSo $500M per year actual sales over 16 years gives $8B total which is just enough to cover costs. No profit.\n\nMeans you need $1B per year potential to even think about a program.\n\n(Which, as you stated, economocally limits targets.)",
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