Sentinel on Nostr: The sad thing is we have only data from mice. Mice die after not eating for 2-4 days. ...

The sad thing is we have only data from mice. Mice die after not eating for 2-4 days. We humans are very special, as our brains need a lot of energy (20 percent of our energy needs go to our brain), so to survive we had to develop the ability to be more ketogenic than most animals and the ability to store fat and use autophagy (e.g., dogs die if they have more than 12 percent body fat, due to heart failure; humans can withstand much, much more fat). As a result, we can last without food for much longer than mice. So the findings there are often not directly translatable.

We have a lot of data about lean body mass being correlated with health, but the longevity data is simply not there. I would be cautious with filling in the blanks prematurely here... at least the way we humans process protein and our needs are completely different from those of rodents. Check out Prof. Layman's research on this topic.