Paul Chambers on Nostr: Brain inflammation may be the reason behind muscle fatigue after infection and injury ...
Brain inflammation may be the reason behind muscle fatigue after infection and injury
Infectious or chronic diseases such as Parkinson's disease, long COVID, Alzheimer’s disease and traumatic brain injury can cause inflammation in the brain, or neuroinflammation, that weakens muscles. While scientists are aware of this link between inflammation and muscle weakness, the molecules and processes involved have been unclear.
A team of neuroscientists and biologists uncovered the hidden conversation between the brain and muscles that triggers muscle fatigue, and potential new ways to treat it.
https://theconversation.com/brain-inflammation-may-be-the-reason-behind-muscle-fatigue-after-infection-and-injury-239817
I have previously learned that microglia, which are immune cells that live in the brain, are the first to respond to injury or infection. The genes that cause PD are expressed in microglia and astrocytes, which can change their role from neuroprotective to pathogenic. In Parkinson's disease, this contributes to the onset and progression of the disease. New treatments could lead to more than just treating fatigue.
Infectious or chronic diseases such as Parkinson's disease, long COVID, Alzheimer’s disease and traumatic brain injury can cause inflammation in the brain, or neuroinflammation, that weakens muscles. While scientists are aware of this link between inflammation and muscle weakness, the molecules and processes involved have been unclear.
A team of neuroscientists and biologists uncovered the hidden conversation between the brain and muscles that triggers muscle fatigue, and potential new ways to treat it.
https://theconversation.com/brain-inflammation-may-be-the-reason-behind-muscle-fatigue-after-infection-and-injury-239817
I have previously learned that microglia, which are immune cells that live in the brain, are the first to respond to injury or infection. The genes that cause PD are expressed in microglia and astrocytes, which can change their role from neuroprotective to pathogenic. In Parkinson's disease, this contributes to the onset and progression of the disease. New treatments could lead to more than just treating fatigue.