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Mitochondrial fatty acid oxidation drives senescence
https://www.science.org/doi/10.1126/sciadv.ado5887
* cellular senescence: stress-induced irreversible cell cycle arrest in tumor suppression/aging
* pharmacological activation of fatty acid oxidation induced senescence in vitro/in vivo
* mitochondrial energy metabolism: critical role in senescence induction
* potential intervention to control senescence
#ageing #aging #senescence #lipids #LipidMetabolism #mitochondria #CellularStress #TumorSuppression #OxidativeStress
https://www.science.org/doi/10.1126/sciadv.ado5887
* cellular senescence: stress-induced irreversible cell cycle arrest in tumor suppression/aging
* pharmacological activation of fatty acid oxidation induced senescence in vitro/in vivo
* mitochondrial energy metabolism: critical role in senescence induction
* potential intervention to control senescence
#ageing #aging #senescence #lipids #LipidMetabolism #mitochondria #CellularStress #TumorSuppression #OxidativeStress